Thymic Development and Selection of T Lymphocytes

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Détails du livre

Titre : Thymic Development and Selection of T Lymphocytes
Pages : 132
Collection : Current Topics in Microbiology and Immunology
Parution : 2013-11-06
Éditeur : Springer
EAN papier : 9783642402517
À propos du livre


The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.

Format EPUB - Nb pages copiables : 1 - Nb pages imprimables : 13 - Poids : 799 Ko - - Prix : 94,94 € - EAN : 9783642402524

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