Role of Capsaicin in Oxidative Stress and Cancer


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Détails du livre

Titre : Role of Capsaicin in Oxidative Stress and Cancer
Pages : 178
Collection : Diet and Cancer
Parution : 2013-04-23
Éditeur : Springer
EAN papier : 9789400763166
À propos du livre

This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mitochondrial cell death pathway.

Format EPUB - Nb pages copiables : 1 - Nb pages imprimables : 17 - Poids : 1772 Ko - - Prix : 94,94 € - EAN : 9789400763173

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